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GLP-1 Receptor Activation: Suppresses appetite through hypothalamic pathways Slows gastric emptying Enhances insulin secretion GIP Receptor Activation: Amplifies GLP-1 satiety effects Improves insulin sensitivity May directly affect fat cell metabolism Glucagon Receptor Activation: Increases energy expenditure (metabolic rate) Promotes fat breakdown (lipolysis) May prevent metabolic adaptation The Advantage: Single molecule means simpler manufacturing, potentially easier regulatory approval, and all three pathways activated with every dose

After oral administration, Deg-AZM was rapidly absorbed into the blood, widely distributed in the tissues without obvious accumulation, and quickly eliminated from the body

In an analysis of similar patients, the risk of heart attack was reduced by 28%

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