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16(5):315-337
1-2H3/b19-9+/t11-
55(4):685-7
selective and cell-permeable p300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 ~400 nM
Hazarika N
Cetirizine D8 dihydrochloride F 8240 16(5):315-337Cetirizine D8 is a deuterium labeled Cetirizine. Cetirizine, a second generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long acting histamine H1 receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response. Product information CAS Number: 2070015 04 0 Molecular Weight: 469. 86 Formula: C21H27Cl3N2O3 Chemical Name: 2 (2 {4 [(4