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Throughout treatment, reassess each patient's risk and frequently monitor for signs and symptoms of abuse, misuse, and addiction

This might include: Keeping a detailed symptom diary during semaglutide initiation Establishing thresholds for concerning symptoms (bloody stools, fever, severe pain) Planning for prompt fecal calprotectin testing or limited sigmoidoscopy if symptoms worsen Scheduling more frequent follow-up during the first 3-6 months of therapy Alternative treatment options should be explored

Some experience vomiting or frequent belching

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Ann Gastroenterol