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BIX 02565 is a novel RSK2 inhibitor with IC50 value of 1 nM
5R)-5-[(1R)-1-hydroxytridecyl]oxolan-2-yl]tridecyl]-2
which contributes to the current understanding of the functional association between PPZ and PKM2(The human M2 isoform of pyruvate kinase)[2]
as this mediator is induced in response to TLR8 activation
having preferential action on K2P2
NCT-502 Catalog No.:M19572-C BIX 02565 is a novelNCT 502 is a human phosphoglycerate dehydrogenase (PHGDH) inhibitor, cytotoxic to PHGDH dependent cancer cells, and reduces glucose derived serine production, with an IC50 of 3. 7 M against PHGDH. Product information CAS Number: 1542213 00 2 Molecular Weight: 395. 45 Formula: C18H20F3N5S Chemical Name: N (4,6 dimethylpyridin 2 yl) 4 [5 (trifluoromethyl)pyridin 2 yl]piperazine 1 carbothioamide Smiles:
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