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32-17(15)16(28)11(27)6-24)31-12-5-22-9-3-2-8(20)14(21)13(9)12
reducing off-target
Epub 2015 Dec 31
Cornett EM
32)23-14-11-21(27)12-15-23)28-26(30)20-9-7-19(8-10-20)18-5-3-2-4-6-18/h2-17
Trilaciclib hydrochloride Catalog No.:M13599-2 32-17(15)16(28)11(27)6-24)31-12-5-22-9-3-2-8(20)14(21)13(9)12Trilaciclib hydrochloride (G1T28 hydrochloride) is a CDK4 6 inhibitor with IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively. Product information CAS Number: 1977495 97 8 Molecular Weight: 519. 47 Formula: C24H32Cl2N8O Chemical Name: 12' {[5 (4 methylpiperazin 1 yl)pyridin 2 yl]amino} 2',5',11',13' tetraazaspiro[cyclohexane 1,3' tricyclo[7. 4. 0. 0,]tridecane] 1'(13'),7',9',11' tetraen 6' one; bis(chlorohydrogen) Smiles: Cl. Cl.