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also known as INC424 and INCB18424 or INCB018424
0 nM) and a very low affinity for the A1 receptors (Ki>10
is structurally similar to tanshinone IIA and may possess similar cytotoxic effects on tumor cells
treatment of cells with HNHA could elicite histone hyperacetylation resulting in an up-regulation of cell cycle arrest
Formula: C26H26N2O7
EP4 receptor antagonist 2 Size:Contact [email protected] for quotation also known as INC424 andEP4 receptor antagonist 2 (compound 2 13) is a potent EP4 receptor antagonist with an IC50 of 7. 8 nM. EP4 receptor antagonist 2 shows antitumor activity. Product information CAS Number: 1965316 82 8 Molecular Weight: 475. 54 Formula: C27H29N3O5 Chemical Name: 4 (4 cyano 2 {[(2'R,4S) 6 [(propan 2 yl)carbamoyl] 2,3 dihydrospiro[1 benzopyran 4,1' cyclopropan] 2' yl]amido}phenyl)butanoic acid Smiles:
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