M-110 0192 ) is rapidly absorpted and

) is rapidly absorpted and distributed in plasma and brain of mice

ON-01910 is a synthetic benzyl styryl sulfone analogue with potential antineoplastic activity

It blocks LPS-induced expression of inflammatory cytokines in human myelomonocytic cells

Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists

Probe Reports from the NIH Molecular Libra

M-110 0192 ) is rapidly absorpted andM 110 is a inhibitor of protein arginine N methyltransferases (PRMTs). It is also a highly isoform selective, cell permeable and potent ATP competitive inhibitor of the PIM kinase family that prefers PIM 3, shown to inhibit the proliferation of prostate cancer cell lines with IC50s between 0. 6 to 0. 9 M, with no activity on normal human peripheral blood mononuclear cells up to 40 M. Product information CAS Number: 1395048 49 3 Molecular Weight: 445.