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By 48 weeks, the gap widens to 24.2% versus approximately 18-19%

This gradual timeline is reflected in real clinical photos, where changes are documented at one month, three months, and six months after the final session

Seek immediate medical guidance if you experience severe or persistent vomiting lasting more than a few hours, signs of pancreatitis (intense upper abdominal pain radiating to your back), rapid heartbeat, or severe allergic reactions (facial swelling, difficulty breathing)

While GLP-1 degradation is unaffected by kidney function, the clearance of both GLP-1, and to a greater extent its inactive metabolites, is delayed in patients with renal insufficiency [184]

Another factor is the loss of muscle mass, which can decrease your overall metabolic rate