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[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Yen K, Lee C, Mehta H, Cohen P

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The Food and Drug Administration (FDA) has not approved Ozempic for weight management, but it has been shown to help manage body weight

Its anti-inflammatory effects include downregulation of pro-inflammatory cytokines (IL-1, TNF-alpha) and modulation of the NF-B pathway

Both classes of agents reduce cardiometabolic risk factors such as HbA1c, body weight, blood pressure and albuminuria, although the effects of GLP-1 receptor agonists on glycemia and body weight are substantially greater than those of SGLT2 inhibitors