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173 The findings from this study further support ghrelins ability to mediate insulinostatic actions, and that reduction in plasma ghrelin could either promote T2D pathogenesis or be an adaptive response to stop further reduction in insulin secretion in T2D patients

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Based on the estimated 3.8 million Part D enrollees eligible for the Medicare GLP-1 Bridge as of 2023, if 10% to 25% participate in Bridge from when the program launches in July 2026 and fill a prescription each month for the 18-month duration of the program, the cost to Medicare would be $1.3 billion to $3.3 billion (at a net monthly cost of $245 minus the $50 beneficiary copay)

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