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6-difluorophenoxy)-3-[[(2R)-3-methyl-2-(quinoline-2-carbonylamino)butanoyl]amino]-4-oxopentanoic acid
CAS Number: 949095-98-1
4-dihydroxyoxolan-2-yl]methyl sulfamate
Formula: C27H40Cl2N6O4S
Brequinar sodium inhibits autophosphorylation of p59fyn with an IC50 of 105 μM
AT 1015 47117096 hydrochloride 6-difluorophenoxy)-3-[[(2R)-3-methyl-2-(quinoline-2-carbonylamino)butanoyl]amino]-4-oxopentanoic acidAT 1015 is a potent antagonist of 5 HT2A receptor . The 5 HT2A receptor is a G protein coupled receptor and a subtype of the 5 HT2 receptor, which belongs to the serotonin receptor family. The 5 HT2A receptor plays an important role in clathrin mediated endocytosis of JC virus, the human polyoma virus which causes progressive multifocal leukoencephalopathy (PML). AT 1015 is a potent 5 HT2A receptor antagonist. AT 1015 bound to 5 HT2 receptors in
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