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Pregnant and breastfeeding individuals have increased requirements for many B vitamins, and indeed these vitamins are routinely included in prenatal supplements

Effect of Methylfolate, Pyridoxal-5'-Phosphate, and Methylcobalamin (Soloways(TM)) Supplementation on Homocysteine and Low-Density Lipoprotein Cholesterol Levels in Patients with Methylenetetrahydrofolate Reductase, Methionine Synthase, and Methionine Synthase Reductase Polymorphisms: A Randomized Controlled Trial

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As with any metabolic peptide, hydration, electrolyte balance, and gradual dose increases are key to minimizing discomfort

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