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Three-times-weekly dosing (Monday, Wednesday, Friday) remains popular, especially for subcutaneous injection

Adequate levels of B-12 are associated with improved mood, mental clarity, and cognitive function

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Two other surrogate markers of B12 deficiency are elevated homocysteine and MCV, although several other nutrient deficiencies can cause these levels to be elevated, so be sure to work with your provider when interpreting any lab test results