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Other known molecular targets of neurosteroids include various TRP channels (151, 152), serotonin receptors and L-Type VGCCs ( 2+ influx via TRPM3 channels in pancreatic beta cells (151)

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The efficacy and safety of the treatment with different combinations versus treatment with either agent alone has been investigated by different groups in large mulitcentral trials [95, 96]

Maugans, T

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